this post was submitted on 19 Nov 2025
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[–] communist@lemmy.frozeninferno.xyz 0 points 3 months ago* (last edited 3 months ago) (1 child)

You sound drunk on kool-aid, this is a validated scientific report from yale, tell me a problem with the methodology or anything of substance.

so what if that's how it works? It clearly is capable of novel things.

[–] just_another_person@lemmy.world 0 points 3 months ago* (last edited 3 months ago) (2 children)

🤦🤦🤦 No...it really isn't:

Teams at Yale are now exploring the mechanism uncovered here and testing additional AI-generated predictions in other immune contexts.

Not only is there no validation, they have only begun even looking at it.

Again: LLMs can't make novel ideas. This is PR, and because you're unfamiliar with how any of it works, you assume MAGIC.

Like every other bullshit PR release of it's kind, this is simply a model being fed a ton of data and running through thousands of millions of iterative segments testing outcomes of various combinations of things that would take humans years to do. It's not that it is intelligent or making "discoveries", it's just moving really fast.

You feed it 10^2^ combinations of amino acids, and it's eventually going to find new chains needed for protein folding. The thing you're missing there is:

  1. all the logic programmed by humans
  2. The data collected and sanitized by humans
  3. The task groups set by humans
  4. The output validated by humans

It's a tool for moving fast though data, a.k.a. A REALLY FAST SORTING MECHANISM

Nothing at any stage if developed, is novel output, or validated by any models, because...they can't do that.

[–] BrundleFly2077@sh.itjust.works 0 points 3 months ago (1 child)

Wow, if you really do know something about this subject, you’re being a real asshole about it 🙄

[–] communist@lemmy.frozeninferno.xyz 0 points 3 months ago (1 child)

He knows the basics, it's just that they don't lead to any of the conclusions he's claiming they do. He also boldly assumes that everyone who disagrees with him doesn't know anything. He's a beast of confirmation bias.

[–] just_another_person@lemmy.world 0 points 3 months ago (1 child)

Nah, I'm just not going to write a novel on Lemmy, ma dude.

I'm not even spouting anything that's not readily available information anyway. This is all well known, hence everybody calling out the bubble.

[–] communist@lemmy.frozeninferno.xyz 0 points 3 months ago* (last edited 3 months ago) (1 child)

You have not said one thing i did not already know, none of it has to do with anything

an ai did something novel, this is an easily verified fact. The only alternative is that somebody else wrote the hypothesis.

[–] just_another_person@lemmy.world 0 points 3 months ago (1 child)

It most certainly did not...because it can't.

You find me a model that can take multiple disparate pieces of information and combine them into a new idea not fed with a pre-selected pattern, and I'll eat my hat. The very basis of how these models operates is in complete opposition of you thinking it can spontaneously have a new and novel idea. New...that's what novel means.

I can pointlessly link you to papers, blogs from researchers explaining, or just asking one of these things for yourself, but you're not going to listen, which is on you for intentionally deciding to remain ignorant to how they function.

Here's Terrence Kim describing how they set it up using GRPO: https://www.terrencekim.net/2025/10/scaling-llms-for-next-generation-single.html

And then another researcher describing what actually took place: https://joshuaberkowitz.us/blog/news-1/googles-cell2sentence-c2s-scale-27b-ai-is-accelerating-cancer-therapy-discovery-1498

So you can obviously see...not novel ideation. They fed it a bunch of trained data, and it correctly used the different pattern alignment to say "If it works this way otherwise, it should work this way with this example."

Sure, it's not something humans had gotten to get, but that's the entire point of the tool. Good for the progress, certainly, but that's it's job. It didn't come up with some new idea about anything because it works from the data it's given, and the logic boundaries of the tasks it's set to run. It's not doing anything super special here, just very efficiently.

[–] markon@lemmy.world -1 points 3 months ago* (last edited 3 months ago)

Start chewing. You literally admitted it in your own comment: "Sure, it's not something humans had gotten to yet." That is the definition of a novel discovery. You are arguing that because the AI used logic and existing data to reach the conclusion, it doesn't count. By that definition, no human scientist has ever had a novel idea either since we all build on existing data and patterns. The AI looked at the same data humans had, saw a pattern humans missed, and created a solution humans didn't have. That is novelty. But honestly it is hard to take your analysis of these papers seriously when you just argued in the comment above that protein folding involves "10^2 combinations." You realize 10^2 is just 100 right? You think complex biology is a list shorter than a grocery receipt. If your math is off by about 300 zeros I am not sure you are the best judge of what these models are actually capable of.

[–] markon@lemmy.world -1 points 3 months ago

​I was almost with you on the whole expert act until the part where you said we feed the model "10^2 combinations of amino acids." ​You realize 10^2 is literally just 100, right? ​You are writing paragraphs acting like the smartest guy in the room, but you think protein folding gets solved by checking a list shorter than a grocery receipt. That is honestly hilarious. ​It kind of explains your whole point though. No wonder you think it is just a "simple sorting mechanism" if you think the dataset is that small. You might want to check the math before the next lecture because being off by about 300 zeros makes the arrogance look a bit silly.